M.A.S Ansari1, Md. Sabbir Hossain2, Amjad Hossain Khan3, Md Shafiqul Hoque Chowdhury4, Farida Khanom5
1. Associate Professor of Pathology, Sylhet Women’s Medical College, Sylhet.
2. Associate Professor of Pathology, North East Medical College, Sylhet.
3. Professor of Pathology, Sylhet Women’s Medical College, Sylhet.
4. Assistant Professor of Pathology, Sylhet M A G Osmani Medical College, Sylhet.
5. Medical Officer of Gynae & Obs, Jalalabad Ragib-Rabeya Medical College, Sylhet
Abstract
The immense medical problems caused by prostate gland are increasing at an alarming rate. The number of cases has continuously increased over the past decades, partly due to the higher life expectancy. Prostatic pathology is one of the commonest disorders causing considerable morbidity and mortality in elderly male population. Benign prostatic hyperplasia (BPH), prostatitis and prostatic cancer are the most common pathological processes affecting prostate. As there has been very little study, if any, carried out on prostatic pathology in Sylhet region, hence we conducted this study on patterns of prostatic diseases based on histopathological specimens. This study can help us to determine various histopathological growth patterns of benign prostatic hyperplasia, age distribution of various prostatic lesions and grading and scoring of prostatic carcinoma according to Gleason’s system. The present study was carried out with an aim to find out the pattern and incidence of different prostatic disorders in Sylhet region. Retrospective study was done during the period of five years and material that included the histopathology slides, the tissue blocks and relevant clinical data were obtained from the department of pathology. In this study BPH was the commonest encountered lesion seen in the prostate (90.8%) and was on many occasions associated with prostatitis. Fibromyoadenomatous pattern was seen to be the commonest growth pattern of BPH. Prostatic adenocarcinoma was found in about (9.2%) of all cases and majority of these cases were of Gleason’s score 4-6. In our study in Sylhet region, Benign prostatic hyperplasia came out to be the commonest prostatic disorder and prostatic adenocarcinoma was the commonest variant of prostatic cancer.
Key Words: Prostate, Prostatitis, Benign prostatic hyperplasia, Prostatic adenocarcinoma.