Tanzil Sajjad1, Abu Yousuf Md Nazim2, Sohel R Chowdhury3, Dhiman Dutt4,
Taharat Fatema Chowdhurys5
1. Assistant Professor, Department of Community Medicine, Sylhet Women’s Medical College, Sylhet.
2. Registrar-Hematology, Department of Medicine, North East Medical College, Sylhet
3. Professor, Research Department, National Heart Foundation Hospital & Research Institute, Dhaka
4. Researcher, Health Manager, Swiss Red Cross, Dhaka
5. Associate Professor, Department of Biochemistry, Sylhet Women’s Medical College, Sylhet
Abstract
Tobacco consumption, hypertension and dyslipidemia are the major risk factors for risk adapted non-communicable diseases, accounting for the highest morbidity and mortality among the Bangladeshi population. The objective of this study was to determine the association between tobacco consumption and changes of serum lipid profiles in hypertensive patients. This cross sectional study was conducted among 308 (202 males and 106 females) hypertensive patients attending in OPD of National Heart Foundation Hospital, Dhaka, Bangladesh between January, 2009 to June, 2009, aged 20 years and older. Among all participants, 46.10% (n = 142) were tobacco smoker, 9.09% (n = 28) were past smoker, 44.80% (n = 138) were never smoked and 28.89% (n = 89) were present smokeless tobacco consumer, 24.35% (n = 7S) were past smokeless tobacco consumer and 46.75% (n = 144) were never consumed smokeless tobacco in their lifetime. Among all the hypertensive participants (n = 308) 28.9% have high total cholesterol (>221 mg%) and 71.1% have normal total cholesterol; 71.4% have low HDL (<36mg %) and 28.6% have normal HDL; 13.3% have high LDL (>151mg %) and 86.7% have normal LDL; 70.1% have high triglycerides (>201mg %) and 29.9% have normal TG. While, the lipid profile of the cigarette smokers (n = 142) group have shown, 29.57% have high total cholesterol and 70.4% have normal total cholesterol; 69.7% have low HDL and 30.3% have normal HDL; 11.3% have high LDL and 88.7% have normal LDL; 78.2% have high TG and 21.8% have normal TG. After computing the Chi-square test it has shown that the tobacco consumption has influence on LDL-cholesterol and TG level which were statistically significant at P-value 0.05. The alteration of lipid profile in smokers has raised serious medical concern with respect to atherogenic risks, ischaemic heart diseases, strokes and other comorbidities. Stringent recommendations regarding counseling the smokers to quit smoking and checking their serum lipid profile at regular intervals should have suggested. Health professionals have the greatest potential of any group in society to promote the reduction of tobacco use. Brief advice from health professionals can increase quitting success rates and intensive advice may increment the chance of quitting tobacco.
Key Words: Serum lipid profile, Tobacco consumption, Hypertension, Total Cholesterol (TC), High density lipoprotein (HDL), Low density lipoprotein (LDL), Triglycerides (TG).