Taharat Fatema Chowdhury1, Ahmad Maksud Hasan Laskar2, Tanzil Sajjad3, Suma Begum4
1. Associate professor, Department of Biochemistry, Sylhet women’s medical college, Sylhet.
2. Associate professor, Department of Surgery, Parkview medical college, Sylhet.
3. Assistant professor, Department of Community medicine, Sylhet women’s medical college, Sylhet.
4. Associate professor, Department of Biochemistry, Sylhet women’s medical college, Sylhet.
Abstract
One of the most important modifiable risk factors in the pathogenesis of cardiovascular disorders such as atherosclerosis hypertension and type-2 diabetes mellitusis obesity. This paper investigated the implication of obesity and plasma lipid profile as indicators for Cardiovascular Diseases (CVD) among the Bangladeshi population. Method: Inferences were drawn from a fully randomized cross-sectional survey, using a sample of 65 male adults aged between 18 to 58 years. Anthropometric measurements, including body weight, height, waist circumference (WC), and body mass index (BMI) were measured and calculated from the subjects. Four groups were created among the respondents under two different categories. Group A (BMI < 25kg / m2) and Group B (BMI > 25kg / m2) Group C (WC< 90 cm) and Group D ( WC > 90 cm). Total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), Low-density lipoprotein-cholesterol (LDL-C), and triglycerides (TG) were also calculated. In comparison with Group A, Group B had higher BMI at 1% significant level. However, Group B had a nonsignificant amplified risk of high TC (P = 0.19) , TG (P = 0.083) and significant amplified risk of high (LDL) (P < 0.01) and low HDL-C (P < 0.001) compared with Group A. Results from Comparing Group C and Group D showed that, Group D had higher WC than Group C at 1% significant level. Moreover, Group D had a significantly amplified risk of high TC (P < 0.05) , TG (P < 0I) LDL-C (P < 0.01) and significantly low HDL-C (P < 0.05) The partial correlation coefficient for the cardiovascular risk marker of BMI indicated a positive non-significant association with TC ( R = 0.21 P >0.05), TG ( R = 0.17 , P > 0.05 ) and LDL-C ( R = 0.25 , P > 0.05 ) and negative association with HDL-C ( R = – 0.26 , P > 0.05 ) For WC indicates a positive statistically significant association with TC R = 0.37 P < 0.05 ) TG (R = 0.34, P < 0.05) and LDL-C ( R = 0, 43 , P < 0.05 ) and negative with HDL-C (R = 0.38, P<0.05). WC is a better indicator of dyslipidemia than BMI.
Key Words: Body mass index, Cardiovascular risks, Lipid profile, Obesity, Waist circumference