Transient Neonatal Hyperglycemia: A Case Report and Review of Literature

Farzana Hamid¹, Syed Moosa MA Quaium², Azizur Rahman³, AT Reza Ahmad⁴, Shahariar Khan⁵, Tania Hussain⁶, Fatematuz Zahra⁷

Abstract
A 10 days old term male baby presented with features suggestive of sepsis for 2 days. Clinically, he was febrile, mildly icteric, tachypnoeic, distended tummy with periumbilical redness and poor reflexes. Partial septic screen was positive along with normal capillary blood glucose and treatment for sepsis was started. But subsequent glucose concentrations over the next 24 hours increased to 14 mmol/L (252 mg/dL), further progressing maximum up to 25.6 mmol/L (460 mg/dL) inspite of changing fluid concentration from 10% to 5% dextrose. So, continuous intravenous insulin infusion was started at a rate of 0.05 unit/kg/hour with a variable period of fluctuation. After 9 days of infusion, blood glucose level was normal and patient’s general condition improved.

Key words: Hyperglycemia, sepsis, neonatal diabetes, insulin therapy.

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