Syeda Umme Fahmida Malik1, A T Reza Ahmad2, Mushfika Rahman Chowdhury3, Begum Najmus Sama Shimu4, Adnan Ibn Shajahan5
1. Associate Professor, Biochemistry, North East Medical College, Sylhet
2. Associate Professor, Pediatrics, North East Medical College, Sylhet
3. Assistant Professor, Biochemistry, North East Medical College, Sylhet
4. Assistant Professor, Biochemistry, North East Medical College, Sylhet
5. Lecturer, Biochemistry, North East Medical College, Sylhet
Abstract
The Energy Balance Study (EBS) was designed to determine the associations of metabolic profile on changes in body weight and composition in a population of healthy men and women over a period of several months. The combined effect of the components of energy balance (energy intake and physical activity) and the development of obesity has not been adequately investigated. The aim of this study was to examine the components of energy balance that will be impactful for our understanding of the roles of energy intake and expenditure on changes in energy utilization and storage. Methods and Results- This is a prospective study of 772 participants who had no prior history of endocrine diseases. Participants completed in-person interviews at baseline follow-up surveys that collected information including dietary and physical activity habits and disease occurrence information. Anthropometric measurements were taken by trained interviewers at recruitment and average follow-up time was 2 and half years. Energy intake (El) was associated with increased risk, while physical activity (PA) was associated with decreased risk of obesity. The EBS recruited 772 healthy men and women aged 20 to 80 years with a BMI of 20-35 kg/m². This study was performed from January 2012 to July 2014 at North East Medical College Hospital(NEMCH). This study shows that subjects with obese (BMI>25) and non-obese (BMI<25) has a significant difference in the biochemical and clinical parameters. Among all subjects with increased BMI Energy Intake is 2186.29±178.884 and Energy Expenditure is 2063.15±165.955 compared with non-obese participant. Energy intake 1870.99+199.745 and Energy Expenditure 1980.60±202.501. So our results suggest that besides the biochemical parameter the degree of obesity influenced by energy balance. This study result will be helpful to understand the impact of the energy balance components as change in body weight depends on the difference between EE and EI. These data suggest that energy balance plays an important role in the development of obesity and this effect may be modified by BMI.
Key words: Body weight, Physical activity, Resting metabolic rate, Energy balance