Mahbub Ul Alam Shumon1, Md. Shahadat Hossain2, Bidhan Chandra Debnath3,Khondaker Serajuddin4, C.M. Reza Qureshi Forhad5, Wajeunnesa6, Roushon Ara Begum7
1. Assistant Professor, Department of Biochemistry, Jalalabad Ragib Rabeya Medical College, Sylhet.
2. Professor, Department of Biochemistry, Sylhet M.A.G.Osmani Medical College.
3. Professor, Department of Biochemistry, Parkview Medical College, Sylhet.
4. Associate Professor , Department of Biochemistry, Sylhet M.A.G.Osmani Medical College.
5. Associate Professor, Department of Biochemistry, US-Bangla Medical College, Rupgonj, Narayangonj.
6. Associate Professor, Department of Physiology, Jalalabad Ragib Rabeya Medical College, Sylhet
7. Assistant Professor, Department of Biochemistry, Sylhet M.A.G.Osmani Medical College.
Abstract
Hereditary hemolytic anaemia is common in south east asia, including Bangladesh & India, that is responsible for considerable morbidity & mortality. In Bangladesh, there is no definite data regarding electrophoretic pattern of hereditary hemoglobin disorders. For this purpose this study was performed to find out the electrophoretic pattern of hemoglobin in hereditary hemolytic anemic patients that was conducted in the department of Biochemistry, Sylhet MAG Osmani Medical College between the period of 1 January 2010 to 30th June 2011. Total 60 diagnosed hereditary hemolytic anemic patients were selected, age ranging from 6 months to 50 years of both sex. This clinoco-haematological study of haemolytic anaemia showed that HbE- thalassaemia were 43.34%, thalassaemia trait 25%, HbE trait 25%, Sickle cell anaemia 3.34%, thalassaemia major 1.67% and HbE disease 1.67%. In this study, it is evident that HbE- thalassaemia is the most common hereditary hemolytic anemia followed by thalassaemia trait & HbE trait.
Keywords: Haemoglobin, hemolytic anaemia, electrophoretic pattern